Monitor for drug dependence, especially in patients with history of substance abuse.• Tell patient that psychological drug dependence may occur.• Instruct patient to avoid over-the-counter drugs and alcohol, because they may increase CNS depression.• Caution patient to avoid driving and other hazardous activities until he knows how drug affects concentration and alertness.• As appropriate, review all other significant and life-threatening adverse reactions and interactions, especially those related to the drugs, tests, herbs, and behaviors mentioned above.adverse effects Among the more serious adverse reactions are ataxia, drowsiness, pronounced weakness, visual disturbances, mental confusion, anaphylactic shock, erythema multiforme, and allergic reactions.Antihistamines, opioids, sedative-hypnotics: additive CNS depression Drug-diagnostic tests. Chamomile, hops, kava, skullcap, valerian: increased CNS depression Drug-behaviors.
Clinical features include anxiety, insomnia, muscle twitching, and hallucinations, and are thought to be due to withdrawal of meprobamate—the main active metabolite of carisoprodol.
When a patient may be physically dependent on carisoprodol, a gradual decrease in dose is required (which might take several weeks for those on high doses).
In 2011, there were over 251 drugs facing some type of supply issue.
Our mission is to help solve the problem with our OUTSOURCING FACILITY (503b) so patients can receive their drugs in a timely manner.
A phased withdrawal of carisoprodol from the UK market will take place.